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Enrolling By InvitationNot applicableNCT05627674
Official study title

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

Study summary

This trial tests the effects of two versions of RiskProfile, a clinically-informed and a genetically-informed version of a patient-specific risk feedback tool, in comparison to usual care, on lung cancer screening and tobacco treatment. The trial assesses the multilevel effects of these precision risk feedback tools on the likelihood of clinicians to order lung cancer screening and tobacco treatment and of their patients to utilize these cancer prevention interventions.

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Key things to know

Main goalPrevention

This describes the study’s primary purpose.

What is being studiedUsual Care and RiskProfile-Clin

Plus 1 other study approaches.

Who it may be forSmoking · Smoking Cessation

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Sep 17, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Enrolling By Invitation

Participation is limited to people invited by the study team.

What kind of study?Not applicable

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?Washington University School of Medicine

Study sponsor

01
Study overview

What this study is about

Purpose
Prevention
Study type
Interventional
Phase
Not applicable
Sponsor
Washington University School of Medicine
Interventions being studied
Behavioral: Usual Care; Behavioral: RiskProfile-Clin; Behavioral: RiskProfile-Gen
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach
Supportive or behavioral care→
03
Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria
  • CLINICIANS: \- Primary care clinician with active caseload in participating clinics PATIENTS:
  • Patient of participating primary care clinician
  • Lung cancer screening naïve
  • Between 50 to 80 years of age, inclusive
  • Current or former smokers
  • Pack years ≥ 20
  • English-speaking
Reasons someone may not be able to joinExclusion criteria
  • PATIENTS:
  • Lung cancer diagnosis
  • Current order placed for lung cancer screening

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Washington University School of MedicineSt Louis, Missouri

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Sep 17, 2026. Always confirm current availability with the study team.

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